| 000 | 03279cam a22005175i 4500 | ||
|---|---|---|---|
| 001 | 21740262 | ||
| 003 | OSt | ||
| 005 | 20220601112742.0 | ||
| 006 | m |o d | | ||
| 007 | cr ||||||||||| | ||
| 008 | 150525s2015 ne |||| o |||| 0|eng | ||
| 010 | _a 2019757869 | ||
| 020 | _a9789401772129 | ||
| 024 | 7 |
_a10.1007/978-94-017-7212-9 _2doi |
|
| 035 | _a(DE-He213)978-94-017-7212-9 | ||
| 040 |
_aDLC _beng _epn _erda _cDLC |
||
| 072 | 7 |
_aPSB _2bicssc |
|
| 072 | 7 |
_aPSB _2thema |
|
| 072 | 7 |
_aSCI007000 _2bisacsh |
|
| 082 | 0 | 4 |
_a572.84 _223 |
| 100 | 1 |
_aZhang, Huidong, _eauthor. |
|
| 245 | 1 | 0 |
_aDNA Replication - Damage from Environmental Carcinogens / _cby Huidong Zhang. |
| 250 | _a1st ed. 2015. | ||
| 264 | 1 |
_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2015. |
|
| 300 | _a1 online resource (XI, 43 pages 4 illustrations, 1 illustrations in color.) | ||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aSpringerBriefs in Biochemistry and Molecular Biology, _x2211-9353 ; _v17 |
|
| 505 | 0 | _aDNA replication -- Disturbances of the DNA replication system -- Fate of DNA replisome upon encountering DNA damage -- External Causes for DNA Damage -- Effect of environmental carcinogens on cellular physiology -- Protocols for studies of bypass of DNA damage by DNA polymerase. | |
| 520 | _aThis book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health. | ||
| 588 | _aDescription based on publisher-supplied MARC data. | ||
| 650 | 0 | _aCell biology. | |
| 650 | 0 | _aNucleic acids. | |
| 650 | 0 | _aPharmacology. | |
| 650 | 1 | 4 |
_aNucleic Acid Chemistry. _0https://scigraph.springernature.com/ontologies/product-market-codes/L14011 |
| 650 | 2 | 4 |
_aCell Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16008 |
| 650 | 2 | 4 |
_aPharmacology/Toxicology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B21007 |
| 776 | 0 | 8 |
_iPrint version: _tDNA replication - damage from environmental carcinogens. _z9789401772112 _w(DLC) 2015940977 |
| 776 | 0 | 8 |
_iPrinted edition: _z9789401772112 |
| 776 | 0 | 8 |
_iPrinted edition: _z9789401772136 |
| 830 | 0 |
_aSpringerBriefs in Biochemistry and Molecular Biology, _x2211-9353 ; _v17 |
|
| 906 |
_a0 _bibc _corigres _du _encip _f20 _gy-gencatlg |
||
| 942 |
_2lcc _cBK _n0 |
||
| 999 |
_c8495 _d8495 |
||