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010 _a 2019740796
020 _a9783319130873
024 7 _a10.1007/978-3-319-13087-3
_2doi
035 _a(DE-He213)978-3-319-13087-3
040 _aDLC
_beng
_epn
_erda
_cDLC
072 7 _aPNFS
_2bicssc
072 7 _aSCI078000
_2bisacsh
072 7 _aPNFS
_2thema
082 0 4 _a543.2-543.8
_223
100 1 _aPottiez, Gwenael.
_eauthor.
245 1 0 _aMass Spectrometry: Developmental Approaches to Answer Biological Questions /
_cby Gwenael Pottiez.
250 _a1st ed. 2015.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _a1 online resource (VIII, 71 pages 12 illustrations)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Bioengineering,
_x2193-097X
505 0 _aGeneral and most usual proteomics methods based on mass spectrometry analysis: Protein identification and protein quantification -- Direct analysis of tissues and body fluids -- Mass spectrometry in archaeology -- Determination and quantification of post-translational modifications -- Protein-Protein interaction determined by mass spectrometry -- Protein structure analysis -- Determination of protein function by mass spectrometry -- Computer-assisted data analysis and data mining for new applications.
520 _aThe understanding of the events taking place in a cell, a biological fluid or in any biological system is the main goal of biology research. Many fields of research use different technology to assess those events. Mass spectrometry is one of those techniques and this undergoes constant evolution and adaptation to always enhance the accuracy of the information provided. Proteomics provides a large panel of data on protein identity and protein expression that were made possible by mass spectrometry. For several years now mass spectrometry has become central to performing proteomic research, however this powerful tool is under constant evolution to be more sensitive and more resolute. More importantly mass spectrometry became a field of research focusing on new applications. Indeed, the complexity in biological systems relies on the changes of expression of transcription of proteins but also on the post-translational modification of proteins, the structure of proteins and the interaction between proteins, amongst others. As of now, several investigations tried to improve the quantification of proteins by mass spectrometry, the determination of post-translational modifications, the protein-protein and protein-nucleic acids interaction or the proteins structures. This book is structured as follows: after a brief introduction of the usual and most popular applications for mass spectrometry in proteomics, the most recent research and developments in mass spectrometry-based methodologies will be explored.
588 _aDescription based on publisher-supplied MARC data.
650 0 _aSpectroscopy.
650 0 _aBiochemical engineering.
650 0 _aMedicine.
650 1 4 _aSpectroscopy/Spectrometry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C11020
650 2 4 _aBiochemical Engineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C12029
650 2 4 _aBiomedicine, general.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B0000X
776 0 8 _iPrinted edition:
_z9783319130880
776 0 8 _iPrinted edition:
_z9783319130866
830 0 _aSpringerBriefs in Bioengineering,
_x2193-097X
906 _a0
_bibc
_corigres
_du
_encip
_f20
_gy-gencatlg
942 _2ddc
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999 _c8494
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