DNA Replication - Damage from Environmental Carcinogens / by Huidong Zhang.

By: Material type: TextTextSeries: SpringerBriefs in Biochemistry and Molecular Biology ; 17Publisher: Dordrecht : Springer Netherlands : Imprint: Springer, 2015Edition: 1st ed. 2015Description: 1 online resource (XI, 43 pages 4 illustrations, 1 illustrations in color.)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9789401772129
Subject(s): Additional physical formats: Print version:: DNA replication - damage from environmental carcinogens.; Printed edition:: No title; Printed edition:: No titleDDC classification:
  • 572.84 23
Contents:
DNA replication -- Disturbances of the DNA replication system -- Fate of DNA replisome upon encountering DNA damage -- External Causes for DNA Damage -- Effect of environmental carcinogens on cellular physiology -- Protocols for studies of bypass of DNA damage by DNA polymerase.
Summary: This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health.
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Item type Current library Call number Status Date due Barcode
Books Books Kwara State University Library Main Library QP624.Z53 2015 (Browse shelf(Opens below)) Available 018873-01
Books Books Kwara State University Library Main Library QP624.Z53 2015 (Browse shelf(Opens below)) Available 018873-02

DNA replication -- Disturbances of the DNA replication system -- Fate of DNA replisome upon encountering DNA damage -- External Causes for DNA Damage -- Effect of environmental carcinogens on cellular physiology -- Protocols for studies of bypass of DNA damage by DNA polymerase.

This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health.

Description based on publisher-supplied MARC data.

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