DNA replication control in microbial cell factories (Record no. 8684)

MARC details
000 -LEADER
fixed length control field 02531cam a22002055i 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140908s2014 nyu 000 0 eng
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783319105321 - pbk
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Author Glinkowska, Monika
245 00 - TITLE STATEMENT
Title DNA replication control in microbial cell factories
Statement of responsibility, etc Glinkowska, Monika; Boss, Lidia; Węgrzyn, Grzegorz;
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication Cham :
Name of publisher Springer,
Date of publication 2015
300 ## - COLLATION
Pagination v, 50p., illus.,
Other physical details includes references
440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE
Series Title Springer Briefs in microbiology
520 ## - SUMMARY, ETC.
Summary, etc This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle
650 ## - TRACINGS
Main Subject 1. ADN Replication Regulation
650 ## - TRACINGS
Main Subject 2. Cellular biology (cytology)
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Main Subject 3. Microbiology (non-medical)
856 41 - ELECTRONIC LOCATION AND ACCESS
URL http://www.loc.gov/catdir/enhancements/fy1501/2014950672-t.html
856 42 - ELECTRONIC LOCATION AND ACCESS
URL http://www.loc.gov/catdir/enhancements/fy1508/2014950672-d.html
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Item type Books
Holdings
Source of classification or shelving scheme Not for loan Permanent location Current location Shelving location Date acquired Accession No. Full call number Barcode. Copy number Koha item type
Library of Congress Classification   Kwara State University Library Kwara State University Library Main Library 2022-10-17 019261 - 01 QP624.5 .G55 2015 019261 - 01 01 Books
Library of Congress Classification   Kwara State University Library Kwara State University Library Main Library 2022-10-17 019261 - 02 QP624.5 .G55 2015 019261 - 02 02 Books